Gemidipine TM 25 Tablet

AboutGemidipine TM 25 Tablet is a combination of Cilnidipine 10mg and Telmisartan 40mg used to treat hypertension (high blood pressure) and provide comprehensive cardiovascular and renal protection.Usage Instructions: Take once daily at the same time, with or without food. Swallow whole with water; do not crush or chew. Continue even if feeling well. Do not stop suddenly without medical advice. Take consistently at the same time daily.Benefits: Effectively lowers high blood pressure with dual mechanism, reduces risk of stroke, heart attack, and cardiovascular death, provides better BP control than monotherapy, provides renal protection and reduces proteinuria (both agents), improves endothelial function, reduces left ventricular hypertrophy, provides 24-hour BP control, suitable for patients with diabetes, chronic kidney disease, or high cardiovascular risk.How it Works: Cilnidipine blocks L-type and N-type calcium channels, causing vasodilation and reducing sympathetic tone. Telmisartan blocks angiotensin II receptors (ARB), causing vasodilation, reducing aldosterone secretion, and providing organ protection. Together they provide synergistic blood pressure reduction through complementary pathways (calcium channel blockade + RAAS inhibition), with enhanced renal and cardiovascular protection.Side Effects: Common: dizziness, headache, fatigue, hypotension, peripheral edema, constipation, nausea, back pain, upper respiratory infection. Serious: severe hypotension, acute kidney injury, hyperkalemia, angioedema (rare), severe allergic reactions, liver dysfunction.Safety Advice: Contraindicated in pregnancy (ARBs cause fetal toxicity), severe kidney disease, or hypersensitivity. Use caution in diabetes, liver disease, or electrolyte imbalances. Monitor blood pressure, kidney function, and potassium levels regularly. May increase potassium; avoid potassium supplements or salt substitutes containing potassium unless prescribed. Inform doctor of dizziness, fainting, muscle weakness, irregular heartbeat, or decreased urination. Maintain adequate hydration.Storage: Store below 25°C in a dry place. Protect from light and moisture. Keep in original packaging. Keep out of reach of children. Do not remove from blister until ready to use.