Upadavio 15MG Tablet

AboutUpadavio 15MG Tablet contains Upadacitinib, a selective Janus kinase (JAK-1) inhibitor used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis.Usage Instructions: Take once daily with or without food. Swallow extended-release tablet whole; do not crush, chew, or split. Take at the same time each day for best results.Benefits: Reduces inflammation and pain in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. Treats moderate to severe ulcerative colitis. Improves physical function, induces remission, and enhances quality of life.How it Works: Upadacitinib selectively inhibits JAK-1 enzyme, blocking signaling pathways of pro-inflammatory cytokines (IL-6, IL-2, interferons, GM-CSF) involved in autoimmune and inflammatory diseases.Side Effects: Common: upper respiratory infections, nausea, headache, acne, increased cholesterol, elevated liver enzymes. Serious: serious infections (TB, fungal, bacterial), blood clots (DVT/PE), malignancy, major cardiovascular events, gastrointestinal perforation, hypersensitivity.Safety Advice: Screen for TB and hepatitis before starting. Avoid live vaccines. Monitor CBC, lipids, and liver enzymes regularly. Report signs of infection, chest pain, leg swelling, or severe abdominal pain immediately. Not for use in pregnancy. Use effective contraception.Storage: Store below 25°C in original packaging. Protect from light, heat, and moisture. Keep out of reach of children.